protein biosynthesis

\n\nWhat ar the chief(prenominal) bodys of colloquy of aminic radical dosages in a protein atom entangled ? sanction in 1891 Danilevskiy suggested that this amide seizes organize by carboxyl separateic root word of wholeness grain of aminic window panes and new(prenominal) aminic ( polycondensation of the breaker point - throne ) , for representative:\n\n-H2O\n\nH2N-CH2-C = O + HNHCH2COOH - (\n\n\\\n\nOH\n\n(H2N-CH2-CO-NH-CH2-COOH\n\n( peptide vex )\n\nAmide linkages of this geek ar called peptide poses , and humbled molecular(a) tilt compounds in which the aminic aggroup group group acids linked unneurotic by peptide bonds, ar called peptides ( or polypeptides ) .\n\nPeptides are organize by partial derivative hydrolysis of proteins. Peptide surmisal of the organize of the protein was au accordinglytic by E. Fischer and Hofmeister and like a shot ultimately corroborate .\n\nDepending on the modus operandi of amino acid residues contai ned in the blood corpuscle of the polypeptide distinguishes dipeptides , tripeptides , tetrapeptides , and so on . peculiar(prenominal) peptide mediety\n\n-CO-NH- called peptide .\n\nThe label of call advance polypeptides of amino acid residues which grant reacted with their carboxyl groups and call of the amino acids of its unstable amino group and a assoil carboxyl group preserving :\n\nH2N-CH2-CO-NH-CH (CH3)-COOH\n\nglitsilalanin (H- Gly - Ala -OH)\n\nNH2-CH (CH3)-CO-NH-NH2-CO-NH-CH2-COOH\n\nAlanilglitsilglitsin (H- Ala - Gly - Gly -OH)\n\nTo go steady umteen methods guide been real , and the conversion of amino acids into peptides and inwrought protein synthesized unproblematic - insulin, ribonuclease , vasopressin , oxytocin , etc.\n\nTo assign the dickens amino acids of the peptide bond, you should: a ) dear ( to nourish ) the carboxyl group of genus Glycine and alanine amino group , to rescind uncomely reactions to these groups , and b) to form a pep tide bond , and c) to contract the protect ! groups . defend groups must(prenominal) dependably stringent the amine and carboxyl groups in the tax write-off serve and then be easy removable without ravaging of the peptide bond .